ENHANCEMENT OF IN VIVO HYPOGLYCEMIC EFFECT OF GLICLAZIDE BY DEVELOPING SELF-MICROEMULSIFYING PELLET DOSAGE FORM

Enhancement of in vivo hypoglycemic effect of gliclazide by developing self-microemulsifying pellet dosage form

Abstract Background The present research was aimed to develop a self-microemulsifying drug delivery system (SMEDDS) pellet to increase the dissolution rate and in vivo hypoglycemic effect of gliclazide.Gliclazide belongs to BCS class 2 and it exhibits dissolution rate-limited absorption.Thus, dissolution enhancement of gliclazide from its dosage fo

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Degos disease: a case report and review of the literature

Abstract Background Degos disease is a very rare syndrome with multisystem vasculopathy of unknown cause.It can affect the skin, gastrointestinal tract, and central nervous system.However, other organs such as the kidney, lungs, pleura, and liver can also be involved.Case presentation A 35-year-old Hindu woman presented to NUTRI B100 COMPLEX our de

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